August, 2010 | Scholarship for Nigerians and Africans - Part 65

PhD Studentship, Synthetic and Structure-Activity Studies on Hemokinin and Analogues, University of Reading, UK

The peptide under initial investigation is hemokinin (HK1), a decapeptide member of the tachykinin family of peptides identified in the mouse with the sequence SRTRQFYGLM-NH2. The equivalent human peptides are termed “endokinins” and differ in a number of subtle ways from hemokinin. The biology of the peptides is not well understood, although it is believed they play an important part in the regulation of the circulatory system. The approach will be twofold involving both organic synthesis and molecular biology. (i) Synthesis of hemokinin analogues will be carried out in proof of concept studies using a novel general ligation strategy developed in the Harwood group that does away with the need for a cysteine residue at the N-terminus, and permits Fmoc protection for generating the C–terminus thioester. (ii) Binding to mouse tachykinin receptors will be studind using radiolabelled HK1 analogues to establish structure activity profiles and identify agonists/antagonists. The analogues will also be studied for their role in platelet function – specifically secretion, integrin affinity modulation and aggregation, and through studying the cell signalling generated by these and the cell lines, develop an understanding of which specific receptors are of importance for the responses observed. These studies mesh with current expertise and interests with the Bicknell and Gibbins groups and might be further extended to endokinin analogues. Applications forms are available from Mrs. Judy Butler, Postgraduate Secretary, Chemistry Department, University of Reading, Whiteknights, Reading, Berks, RG6 6AD, Telephone Number: 01183786591 or by email j.m.butler@reading.ac.uk. Application Deadline October2010 Read more: http://scholarship-positions.com/phd-studentshipsynthetic-and-structure-activity-studies-on-hemokinin-and-analoguesuniversity-of-reading-uk/2010/08/10/?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+ScholarshipPositions+%28International+Scholarships+and+Financial+Aid+Positions%29&utm_content=Yahoo%21+Mail#ixzz0x8foh5VQ

Postdoctoral Researcher in Non-Equilibrium Statistical Mechanics, UK

We offer a 3-year post-doctoral position in Non-Equilibrium Statistical Mechanics within the interdisciplinary group led by Dr. Lucarini. The position is funded through the EU-ERC project NAMASTE.

The research will focus on the analysis of the statistical mechanical properties of the climate systems using theoretical tools and models of various degrees of complexity. Attention will be devoted to the rigorous analysis of the response of the system to perturbations. The impact of stochastic forcings will also be addressed.

Informal contact details

Contact role: Principal Investigator

Contact name: Valerio Lucarini

Contact phone: +44 (0)118 3785573

Contact email: v.lucarini@reading.ac.uk

We invite you to apply online for this vacancy by clicking the link at the bottom of this page.

Alternatively, if you wish to apply using a hardcopy form please email recruitment@reading.ac.uk or contact Human Resources, University of Reading, Whiteknights, PO Box 217, Reading RG6 6AH or Telephone +44(0)118 378 6771 (voicemail).

Application closing date 03/09/2010

Postdoctoral Research Fellow inLearning and Digital Technologies, Norway

MIRACLE aims to improve science education and the link between schools and science museums by designing a flexible, open-ended learning environment that truly engages and empowers adolescent learners. In the planned MIRACLE learning platform students embark on authentic missions that can be completed through productive learning activities. The MIRACLE platform will be a system for collaborative and productive learning and teaching of science through use of a flexible and adaptive pedagogical approach to learning based on different kinds of knowledge representations (including 3D).

The MIRACLE project is headed by InterMedia, University of Oslo, and InterMedia also designs and evaluates the learning platform. The post-doctoral fellow will be part of the Design of Information Systems group at the Department of Informatics and will work with questions related to design and evaluation of the MIRACLE learning platform particularly concerned with representations in science education. Questions concerned with representation of abstract knowledge are also research topics in The Design of Information Systems group. For this post-doctoral fellowship we value interdisciplinary backgrounds high, in particular combinations of informatics and design of information systems with education/learning sciences, psychology, anthropology and/or sociology.

As part of the appointment, a limited amount of teaching, supervision, or other non-research duties may be assigned (10%).  This position is part of a new research project, with funding from the Norwegian Research Council and additional third year funding from Department of Informatics, University of Oslo.

Requirements:

The candidate must have a PhD or other corresponding education equivalent to a Norwegian doctoral degree in informatics or an interdisciplinary degree with a large component of informatics. Applicants are expected to include a summary of academic specialization and statement of scientific interests. For background on the research environment, please see:http://www.ifi.uio.no/research/groups/design and http://dis.ifi.uio.no/a3

UiO (and Norway more generally) is a multi-lingual environment, where knowledge of Norwegian is not a necessity in everyday life. However, a good command of English is required. http://www.matnat.uio.no/english/research/education/proficiency_in_English.html

The main purpose of post-doctoral research fellowships is to qualify researchers for work in top academic positions within their disciplines. As part of the appointment, a limited amount of teaching, supervision, or other non-research duties may be assigned (10%). No one can be appointed for more than one period at the same institution.

Please also refer to the regulations pertaining to the conditions of employment for post-doctoral fellowship positions:

http://www.uio.no/admhb/reglhb/personal/tilsettingvitenskapelig/regulationstermcondition.xml

The application must include:

  • Application letter
  • Statement of research interest
  • CV (summarizing education, positions, pedagogical experience, administrative experience and other qualifying activity)
  • Copies of educational certificates, transcript of records and letters of recommendation, as applicable
  • A complete list of publications and up to 5 academic work that the applicant wishes to be considered by the evaluation committee
  • Names and contact details of 2-3 references (name, relation to candidate, e-mail and telephone number

Foreign applicants are strongly advised to attach an institutionally issued explanation of their University’s grading system. Please remember that all documents should be in English or a Scandinavian language.

Closing date for applications: August 20, 2010.