Grants and Fellowships | Scholarship for Nigerians and Africans - Part 129

PhD Researcher within the Biomarine Sciences Group, Netherlands

Project title: “Double trouble: Consequences of Ocean Acidification – Past, Present and Future: Dinoflagellate Component.

Along with climate warming, anthropogenic CO2 is currently causing a significant increase in ocean acidity: Double Trouble! The effects of ocean acidification on marine calcifying organisms and plankton, as well as the marine carbon cycle are still poorly understood. The present research program constitutes an integrated multidisciplinary approach, combining (1) laboratory experiments using organisms grown under CO2 controlled conditions (2) reconstructions of ocean acidification in the geological past, and (3) studies of the impact of ocean acidification on the marine carbon cycle. Together this will quantify the impact of ocean acidification on calcification and feedbacks on atmospheric CO2 levels. The impact of past ocean acidification on evolution and extinction will provide important constraints on the adaptation potential of marine calcifying organisms and non-calcifying plankton. Furthermore, results will allow for determining the consequences for the marine carbon cycle.

The project, which involves 3 PhD students and one Postdoctoral researcher, is a collaborative project of the Biology and Earth Sciences departments at Utrecht University, the Netherlands Institute for Sea Research (NIOZ), and the Alfred-Wegener Institute for polar and marine research (AWI) in Bremerhaven, Germany. The project is sponsored by the Darwin Center for Biogeology.

Dinoflagellates are protists and are ubiquitous in all aquatic environments. They comprise a vital component of the total eukaryotic primary production in the oceans. Approximately 15% of the dinoflagellates exhibit a complex life cycle that includes the formation of an organic cyst. These cysts preserve well in sediments deposited under relatively low oxygen conditions (their fossil record goes back to the Late Triassic, ~215 million years ago), and have been widely applied in biostratigraphic and paleoenvironmental studies. Here we initiate a novel avenue in dinoflagellate research involving their stable isotope chemistry. Pilot studies have indicated that the differential incorporation of the stable isotopes 12C and 13C into dinoflagellates and their cysts is related to the CO2 concentration, and as such pH, of seawater. We aim to develop this relation into a new proxy for surface ocean carbon speciation using culturing experiments and test the relation using the past 150 years. The study will involve culturing of several dinoflagellate species with a long fossil range under various CO2 and pH conditions. Both the motile and cyst stages will be analyzed for stable isotope and associated biochemistry. Fossil cysts will be analyzed for their chemistry for the reconstruction of past ocean acidification events, such as the Paleocene/Eocene boundary (PETM, ~55 million years ago).

The primary place of work is Utrecht, The Netherlands. Components of the research will be carried out at the AWI, where the candidate will spend several stays of several months.
Qualifications

We seek a highly motivated candidate with excellent communication skills with experience in Biology or Biogeology, an MSc in an appropriate field and interest in experimental research (including culturing experiments) on the boundary between Biology and Earth Sciences. Candidates are expected to communicate easily in English, both verbally and in writing.
Terms of employment

The successful candidate will be offered a full-time PhD position for a period of four years. The salary is supplemented with a holiday bonus of 8% and an end-of-year bonus of 8,3% per year. In addition we offer: a pension scheme, a partially paid parental leave, flexible employment conditions. Conditions are based on the Collective Labour Agreement Dutch Universities. The research group will provide the candidate with necessary support on all aspects of the project. More information on conditions is available here.

Further details:

Additional information about the vacancy can be obtained from: Dr Appy Sluijs, email: A.Sluijs@uu.nl. As part of the selection procedure, the candidate is expected to give an outline of his/her research plans in a written report and an oral presentation. You may also wish to visit the websites of the Department of Biology, the Institute of Environmental Biology, the Biomarine Sciences group, the Alfred Wegener Institute and the Darwin Center for Biogeosciences.

How to apply:

Please send your application (including a letter of motivation, curriculum vitae and contact details of at least two references) before September 20th, 2010 to email: Science.PenO@uu.nl. Please mention vacancy number 66009.

Postdoctoral Scientist in Cystic Fibrosis and Calcium Signaling Research,University of Bretagne Occidentale, France

: A 12-month post-doctoral position in the area of ion channel physiology and calcium signaling funded by the Conseil Général du Finistère is available for January 2011 in the INSERM unit U613 located in the Medical Center of the University of Bretagne Occidentale in Brest (France).
This postdoctoral position is opened in the lab of Dr. Olivier Mignen to investigate the molecular and cellular mechanisms underlying calcium signaling in mammalian cells and its implication in Cystic fibrosis.
Our laboratory is mainly interested in understanding the molecular mechanisms underlying calcium entries in non excitable cells and their roles in health and disease. Calcium entry is essential for many cellular functions including gene expression, secretion, cell motility and cell proliferation and differentiation. We are investigating the molecular components and the control mechanisms of store dependent and store independent calcium entries.
The main objective of the project is to characterize in airway epithelial cells the calcium signaling pathways involved in ion secretion and the potential beneficial roles of their stimulation to counteract the defect of chloride secretion observed in cystic fibrosis. The postdoctoral scientist will also be involved in studies designed to identify protein partners of calcium channels involved in calcium entry and pharmacological modulators of these entries. The knowledge derived from our research may ultimately lead to design novel pharmacological agents to treat Cystic fibrosis. Our project combines different experimental approaches including live-cell imaging, biochemistry, molecular biology and electrophysiology.
Extremely motivated Ph.D.s (maximum of 4 years postdoctoral experience) with a strong background in molecular and cell biology are encouraged to apply. Candidates with demonstrated records in studying calcium signaling will be preferred. Experiences in electrophysiology would be an asset but is not required. The candidate should have proven skills in Western blotting, immunoprecipitation, real time PCR, immunofluorescence, immunohistochemistry, cell culture techniques and in vitro transfection. Additional preferred skills include live cell confocal microscopy and proteomics. Knowledge of the physiology of fluid-secreting epithelia will also be appreciated. The applicant must be enthusiastic with communication skills (English and/or French) in order to be able to join a young starting team located in an excellent environment of research with various state-of-the-art core facilities. The applicant will collaborate with the other members of the unit and must show a high motivation interdisciplinary work. The applicant must have done its PhD outside Britany and defended his thesis less than 4 years ago.
Salary ~ 2000€/month.
Contact Person:
Olivier Mignen
INSERM U613 – IFR148 ScInBioS
Faculté de Médecine et des Sciences de la Santé
22 avenue Camille Desmoulins
F-29200 BREST -FRANCE
tel.: + 33 (0)2 98 01 67 05
fax. : + 33 (0)2 98 01 82 29
e-mail: olivier.mignen@univ-brest.fr
visit our webpage: http://www.genetic-brest.fr/

or

Aurélie Vandebrouck
INSERM U613 – IFR148 ScInBioS
Faculté de Médecine et des Sciences de la Santé
22 avenue Camille Desmoulins
F-29200 BREST -FRANCE
tel.: + 33 (0)2 98 01 81 98
fax : + 33 (0) 2 98 01 82 29
e-mail : aurelie.vandebrouck@univ-brest.fr

Research Scholarships, Mody Institute of Technology and Science, India

Applications enclosing biodata are invited from both male and female candidates to work as, Project Assistant Level-2, 1 Nos.  in the project, ‘Prevention and Control of Fluorosis in Lakshmangarh using Low Cost Defluoridation Filters’. The project Chemistry Project Assistant Level 2 is sponsored by DST, New Delhi and is in collaboration with the IISc Bangalore under the aegis of DST Rajasthan, Jaipur. The position is purely temporary and are coterminous with the project (3 years). PI: Dr. Kushal Qanungo, Assoc. Prof. (Chemistry) MITS, Co-PI-1: Dr. Sudhakar M. Rao, Prof. (Dept of Civil Engg.) IISc Bangalore, Co-PI-2: Dr. Saroj K. Sharma, Asst. Prof. (Physics) MITS.

Eligibility Criteria: M.Sc. Chemistry,Env. Sci. 1st Div.
Age Limit: 28 years
Closing Date: 15 august 2010
Applications must be sent by e-mail at the address: kushalq@hotmail.com Please mention the position applied for, in the subject line of the email. Applications will be recieved till post is filled up. Preference will be given to candidates who can join immediately. Age limit 28 years. The work involves some fieldwork also.
Contact Person: Dr. Kushal Qanungo, Faculty of Engineering and Technology, Mody Institute of Technology and Science (Deemed University), Lakshmagarh-332311, Dist. Sikar, Rajasthan. Tel: 01573- 225001(12 Lines) ext. 425(W), ext. 306 (H) Fax -01573 225042, M 9829355893