Medical Science | Scholarship for Nigerians and Africans - Part 165

PhD fellowships in the Faculty of Pharmaceutical Sciences, Denmark

Applications are invited for the three-year fellowships from candidates that hold or expect to hold a master’s degree in a field relevant to the following projects:

1. Drug Delivery
Cubosomes and hexosomes as drug nanocarriers. Main supervisor: Associate Professor Anan Yaghmur, Department of Pharmaceutics and Analytical Chemistry (email: aya(at)farma.ku.dk).

2. Optimal Drug Therapy
Adverse drug reactions and pharmacogenomics: Improving knowledge about medicines safety. Main supervisor: Associate Professor Lise Aagaard, Department of Pharmacology and Pharmacotherapy (email: laa(at)farma.ku.dk).

3. Optimal Drug Therapy
Computational simulation of rule-based adaptive regulation in circulation. Main supervisor: Associate Professor Harrie C. Boonen, Department of Pharmacology and Pharmacotherapy (email: hcmb(at)farma.ku.dk).

4. Neuropharmacology
Novel role of Ca2+ for regulating cellular brain bioenergetics. Main supervisor: Associate Professor Lasse Bak, Department of Pharmacology and Pharmacotherapy (email: laba(at)farma.ku.dk).

5. Medicinal Chemistry – Structure-Based Drug Research
Design and synthesis of the first selective ligands for the GPRC6A receptor – a novel human G-protein coupled receptor with unknown physiological function.
Main supervisor: Professor Hans Bräuner-Osborne, Department of Medicinal Chemistry (email: hbo(at)molpharm.net).

6. Medicinal Chemistry – Structure-based Drug Research
Elucidating the structure and mechanism of proton coupled peptide transporters.
Supervisor: Associate Professor Osman Mirza, Department of Medicinal Chemistry (email: om(at)farma.ku.dk).

7. Drug  Delivery – Pharmaceutical Technology
In vivo and in vitro gastric physico-relevant dissolution.
Main supervisor: Associate Professor Anette Müllertz, Department of Pharmaceutics and Analytical Chemistry (email: amu(at)farma.ku.dk).

The project is cofinanced by the Faculty of Pharmaceutical Sciences and AstraZeneca Mölndal, Sweden.

8. Drug Delivery – Pharmaceutical  Technology
Rational development of oromucosal drug delivery systems by use of predictive in vitro models.
Main supervisor: Associate Professor Jette Jacobsen, Department of Pharmaceutics and Analytical Chemistry (email: jeja(at)farma.ku.dk).

The project is cofinanced by the Faculty of Pharmaceutical Sciences and the Innnovation Consortium “Predicting Drug Absorption”.

The PhD fellowships are to be completed in accordance with the Ministerial order on the PhD programme at the universities (PhD order) from the Ministry of Science, Technology and Innovation and the Regulations and guidelines for the conferment of the PhD degree by the Faculty of Pharmaceutical Sciences. The terms of employment are stated in the agreement between The Danish Confederation of Professional Associations and the Ministry of Finance.

As an equal opportunity employer, the Faculty of Pharmaceutical Sciences invites applications from all interested candidates regardless of gender, age, ethnic origin or religion.

For further information, applicants may contact the main supervisor.
How to apply

Step One: Make one pdf-file (max 10 mb) with the following contents:

1. Letter stating the interest and qualifications for the project (max. one page)
2. CV
3. Master’s degree diploma (including grade transcripts for bachelor’s and master’s degrees)
4. Possible publication list
5. Possible references
6. Applicants with a Master’s degree from abroad should also enclose a short description of the grading scale used.

Step Two: Fill in the following form and upload the pdf: Application form

Step Three: Print the pdf-file and send one hard copy in an envelope marked “Reference 211-0042/10-0900″ to:

University of Copenhagen
Faculty of Pharmaceutical Sciences
Universitetsparken 2
DK – 2100 Copenhagen
Denmark

The hard copy has to be received at the Faculty of Pharmaceutical Sciences before the application deadline.

Deadline for applications: Monday 30 August 2010 at 12 o’clock noon.
Read more: http://scholarship-positions.com/phd-fellowships-in-the-faculty-of-pharmaceutical-sciences-denmark/2010/08/05/?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+ScholarshipPositions+%28International+Scholarships+and+Financial+Aid+Positions%29&utm_content=Yahoo%21+Mail#ixzz0xVnoDVw9

Postdoctoral Position Ambulatory Real-time Detection of Major Epileptic Seizures, Netherlands

Technische Universiteit Eindhoven (TU/e) is one of Europe’s leading research universities. The Eindhoven area, in the southern part of the Netherlands, is one of Europe’s top ‘innovation ecosystems’, with many high-tech companies and institutes. TU/e is closely intertwined with many of these companies and institutes, and research at TU/e is characterized by a combination of academic excellence and industrial relevance. Culturally, the Netherlands is a very interesting part of Europe. Historic cities such as Amsterdam, The Hague, Maastricht, Brussels, and Antwerp are all within easy reach from Eindhoven.

Kempenhaeghe is an internationally leading expertise centre for epilepsy and sleep-wake disorders. Kempenhaeghe is involved in nearly all major domains of epilepsy research, and offers a multidisciplinary semi-academic clinical research environment in the Eindhoven area. One of the innovation programmes in the area of diagnosis focuses on the detection of epileptic events, called seizures.

Project description

The goal of the ‘seizure detection programme’ is to achieve increased safety for the patient and a better quality of life for them and their loved ones by offering reliable, unobtrusive detection of epileptic seizures. Epilepsy has many different types of seizures, ranging from minor very short to major life-threatening seizures; every type has its own characteristics. The golden standard for detection of epileptic seizures uses combined EEG and video monitoring. This process is time-consuming, expensive, and only applicable to hospitalized patients. In order to overcome these problems and widen the reach of seizure detection to extramural patients, dependable unobtrusive approaches are critically needed. In past collaborative research, Kempenhaeghe and TU/e have gained important experience in detecting seizures based on analysis of heart activity and based on accelerometers attached to various parts of the body. Building on this experience, this PostDoc project seeks to develop and validate an unobtrusive system for detection of major epileptic seizures, and to iteratively refine it to approach the dependability of the aforementioned golden standard.

The main scientific focus will be on the development of dynamic models that characterize epileptic heart activity, epileptic movements, and the key sensor characteristics and (e.g. movement) artifacts, along with sophisticated multimodal model-based signal-processing and interpretation algorithms to extract reliable seizure information in ambulatory settings. The project will take a clinically driven approach, i.e. working in close collaboration with neurologists and medical technicians and taking their experience and knowledge as starting point. Algorithm development and validation will be based on real clinical data from patients. To obtain adequate clinical immersion, the candidate is expected to spend a significant fraction of his/her time at Kempenhaeghe, while TU/e will be the home base for algorithm development.

Requirements

Candidates for this position should have a Ph.D. degree in signal processing or control, physics, or biomedical engineering, and an extensive publication record in leading journals. A strong mathematical basis and a background in signal processing (statistical and adaptive signal processing, pattern recognition and machine earning, efficient real-time implementation of signal processing algorithms) is required. Hands-on experience with physiological monitoring and ambulatory sensor systems is desired, as are good programming skills in Matlab and C++. Candidates should be pro-active and entrepreneurial, have a ‘hands-on’ attitude, and excellent social and team working skills.

What we offer

A challenging job with a combined appointment at a multidisciplinary clinical expertise centre and a dynamic and ambitious University. A temporary appointment for the period of 3 years. Gross monthly salaries are in accordance with the Collective Labor Agreement (CAO) and are at least € 2988 per month (FWG 60) and at most € 4705 per month (scale 12). Salary is based on knowledge and experience. An attractive package of fringe benefits (including excellent work facilities, child care, and excellent sports facilities).

Application Deadline 29-08-2010.
Read more: http://scholarship-positions.com/postdoctoral-position-ambulatory-real-time-detection-of-major-epileptic-seizures-netherlands/2010/08/04/?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+ScholarshipPositions+%28International+Scholarships+and+Financial+Aid+Positions%29&utm_content=Yahoo%21+Mail#ixzz0xQvofvqm

Postdoctoral Position in “Tissue Integrity of the Intervertebral Disc”, Netherlands

The Department of Biomedical Engineering is a joint department of the Eindhoven University of Technology and the University of Maastricht interfacing and integrating engineering and biomedical sciences from the two universities. The department is organized into 4 divisions: 1) molecular bioengineering, 2) biomechanics and tissue engineering, 3) biomedical imaging and informatics, and 4) biosignals and regulation.

In the second division is the Orthopedic Biomechanics Section whose general objective is to improve our understanding of function and damage of orthopedic tissues, esp. bone, cartilage and intervertebral disc. Ultimately, these insights are used to develop and improve strategies for treatment of pathologies. For this purpose, we regularly combine experimental and computational approaches. Results from experimental studies on cells and/or tissues are captured in theories that are evaluated using computer models, and predictions by these models are helpful for the design and interpretation of further experiments.

Project description:

Degeneration of the intervertebral disc is a common, painful and disabling pathology whose etiology and pathogenetic mechanism is poorly understood. It is generally believed that genetic, cell nutrition and biomechanical factors play a key role; however the interactions between them have been difficult to investigate because of the inherent limitations of current cell and organ culture methods. Among the genetic factors, collagen IX polymorphisms have been identified as a risk factor. In this project, the role of collagen IX will be investigated on the nanoscopic level in collagen gels of chicken. Optical tweezers will be used to analyse the influence of collagen IX upon a collagen network down to the individual fibril level. The resulting finding will be built into an existing FE-model of the degenerating disc.

Requirements:

We are seeking a Post Doc candidate acquainted with optical techniques in biomedical engineering and interested in biological processes and modeling of them. The candidate should be graduated from a Ph.D. program in biomedical engineering, (bio)physics or a related field, with,

* Knowledge of and experience with optical techniques in biomedical engineering,
* Strong affinity for multidisciplinary research and engineering science,
* Capacity to write and communicate fluently in English.

Appointment and Salary:

We offer:

* a challenging job at a dynamic and ambitious University
* an appointment for one year, with the possibility of extension with one year.
* gross monthly salaries are in accordance with the Collective Labor Agreement of the Dutch Universities (CAO NU), For the PD position it is increasing from € 2.861 per month initially, to € 2.977 in the second year
* an attractive package of fringe benefits (including excellent work facilities, 13th month salary, holiday allowance of 8%, child care and sport facilities).

Application Deadline 31-08-2010.