carcinogenesis | Scholarship for Nigerians and Africans - Part 3

PhD and Post-Doc Positions in Tumor Immunology Research, Israel

M.Sc. / Ph.D. students and Post-Doctoral fellows are invited to join the laboratory of Cytokine Biology, in the Shraga Segal Department of Microbiology and Immunology, Faculty of Health Sciences
Major scientific projects of the laboratory include:
1). The role of inflammation in the malignant process (carcinogenesis, tumor invasion and metastasis, tumor angiogenesis and interactions of
the tumor with the host’s immune system).
2). Interleukin-1 (IL-1) receptor and Toll-like receptor (TLR) signaling in sterile inflammation and angiogenesis in the malignant
process.
3). Mechanisms and signaling pathways of novel intracellular non-secretable aisoforms of the cytokine IL-1.
4). Intervention in IL-1 expression in anti-tumor therapeutic approaches.
Techniques used in the laboratory include tissue culture and in vitro
work, molecular biology techniques and in vivo work. These are applied to cutting-edge issues in cytokine and tumor immunobiology, stem cell biology and angiogeesis. Excellent teamwork and atmosphere
Excellent Students could apply to the “Bio medicine Challenges” program for generous funding of the degree and full stipend.

Scholarship Application Deadline: Contact Employer
Further Scholarship Information and Application

PhD Student for Molecular Carcinogenesis, Netherlands: Biomedical Sciences

Recurring chromosomal abnormalities have been identified in a variety of cancers, but are most frequently associated with haematological malignancies such as acute myeloid leukemia (AML). These cytogenetic changes often cause gene fusions leading to expression of chimeric oncofusion proteins. In this project you will focus on unravelling the role of these oncofusion proteins in carcinogenesis. Your aim will be to identify the binding regions, the transcriptional consequences and epigenetic features associated with oncofusion protein expression. You will use next-generation sequencing to identify oncofusion protein target sites, which then will be further characterized, structurally as well as functionally, in relation to the aetiology of acute myeloid leukemia.

Requirements
You should have:
• an MSc degree in Biomedical Sciences/Biology/Molecular Life Sciences/Bioinformatics;
• experience in Molecular and Cell Biology and/or Bioinformatics;
• a strong affinity for fundamental research related to human disease;
• a well-structured working style;
• well-developed social and communication skills.

Conditions of employment
Employment: 1,0 fte
Maximum salary per month, based on a fulltime employment: € 2,612 gross/month
The starting salary is € 2,042 per month and will increase to € 2,612 per month in the fourth year. PhD scale.
Duration of the contract: 4 years
Scholarship Application Deadline: 14 January 2011
Further Scholarship Information and Application