molecular genetics | Scholarship for Nigerians and Africans

LGSA PhD Positions 2011, Germany: Ageing and Age-Related Diseases

The Leibniz Graduate School on Ageing and Age-Related Diseases (LGSA) is a joint programme of the Leibniz Institute for Age Research – Fritz Lipmann Institute (FLI) and the Friedrich – Schiller – University (FSU) in Jena. The School calls for applications for PhD positions available in spring/ summer 2011.

The Leibniz Graduate School on Ageing offers an international postgraduate programme for students with excellent qualifications. The participating research groups work on Molecular Biology, Molecular Genetics, Cell Biology, Developmental Biology, Cancer Biology, Neurobiology and Structural Biology to investigate the multifaceted mechanisms that cause the development of age-related diseases and those that cause senescence and ageing.

Training and research within the PhD program is interdisciplinary. Lecture series, seminars, journal clubs and courses as well as training in presentation skills and language classes complement the practical work. A thesis committee provides comprehensive support and the mentorship in the career development of the student. The programme language is English. The salary will be according to German TV-L E 13 (salary agreement for public service employees – 50 % position during the first and second year and a 60 % position during the third and fourth year).

Eligible are students that have obtained, or that will obtain within half a year, an academic degree comparable to the master degree or diploma in natural sciences (e.g. Biology, Biochemistry, Physics, and Chemistry).

For the first step please acquaint yourself with the research of the participating groups and with the application procedure on our website (Application), download the application and recommendation forms, fill in the application form and send it electronically to the LGSA (the email address can be found in the application guidelines). Forward the recommendation form to two referees and ask them to submit their letter directly to the LGSA. Applicants should carefully follow the application guidelines. Do not submit your documents to the research group leaders. Incomplete or non-fitting applications will not be considered.

Scholarship Application Deadline: 10 April 2011

Further Scholarship Information and Application

University of Cambridge, Phd Studentship in Pathogen Cell Biology 2011 in UK

Bacterial pathogen subversion of the mammalian actin cytoskeleton

Applications are invited for a PhD studentship, supervised by Prof. Vassilis Koronakis, to research mechanisms underlying bacterial pathogen subversion of the mammalian cytoskeleton. Actin polymerisation is mediated by a complex signalling network requiring small G-protein activation that target N-WASP and the SCAR/WAVE complex to initiate Arp2/3-dependent actin nucleation. The detailed processes by which cellular signal transduction cascades lead to the formation of discrete actin structures remain unresolved. These signalling pathways are hijacked by pathogens like Salmonella and E.coli to promote colonisation, survival and dissemination, deploying virulence (effector) proteins to manipulate host actin dynamics.

The student will dissect key eukaryotic signalling networks targeted by these bacterial pathogens using a multidisciplinary approach involving the culture and infection of mammalian cells, cell biology, fluorescence microscopy, protein biochemistry and molecular genetics. Detailed characterisation of the mechanisms underlying actin polymerisation will not only reveal the molecular basis of disease, but also illuminate fundamental processes in cell biology.

Experience and/or Masters degree is desirable.

How to apply:

Applicants should hold or be about to achieve a First or Upper-Second (2.i) class degree in a relevant subject. Experience and/or Masters degree is desirable.

Shortlisted candidates will be required to formally apply through completion of a Graduate and Scholarship Application Form (GRADSAF) before attending interview.

Applications from ineligible candidates will not be considered.

Application Deadline: 28 February 2011.

Further Scholarship Information and Application

University of Cambridge, Phd Studentship in Pathogen Cell Biology 2011 in UK

Bacterial pathogen subversion of the mammalian actin cytoskeleton

Applications are invited for a PhD studentship, supervised by Prof. Vassilis Koronakis, to research mechanisms underlying bacterial pathogen subversion of the mammalian cytoskeleton. Actin polymerisation is mediated by a complex signalling network requiring small G-protein activation that target N-WASP and the SCAR/WAVE complex to initiate Arp2/3-dependent actin nucleation. The detailed processes by which cellular signal transduction cascades lead to the formation of discrete actin structures remain unresolved. These signalling pathways are hijacked by pathogens like Salmonella and E.coli to promote colonisation, survival and dissemination, deploying virulence (effector) proteins to manipulate host actin dynamics.

The student will dissect key eukaryotic signalling networks targeted by these bacterial pathogens using a multidisciplinary approach involving the culture and infection of mammalian cells, cell biology, fluorescence microscopy, protein biochemistry and molecular genetics. Detailed characterisation of the mechanisms underlying actin polymerisation will not only reveal the molecular basis of disease, but also illuminate fundamental processes in cell biology.

Experience and/or Masters degree is desirable.

How to apply:

Applicants should hold or be about to achieve a First or Upper-Second (2.i) class degree in a relevant subject. Experience and/or Masters degree is desirable.

Shortlisted candidates will be required to formally apply through completion of a Graduate and Scholarship Application Form (GRADSAF) before attending interview.

Applications from ineligible candidates will not be considered.

Application Deadline: 28 February 2011.

Further Scholarship Information and Application