We are interested in the underlying mechanisms governing the properties of normal and malignant stem cells. Our main focus is, very broadly, how the control of gene expression contributes to the biology of normal hematopoietic stem cells and how this control is altered in acute myeloid leukemia.
Research in the group involves the use of a number of experimental systems including human patient samples as well as genetically modified mouse models. We have strong expertise in multicolor flow cytometry and use a number of genomic techniques – such as ChIP-seq to assess transcription factor binding and epigenetic configurations as well as micro array and sequencing-based (RNA-seq) gene expression profiling. Importantly, the interpretation of these data is supported by a number of “in-group” bioinformaticians as well as extensive collaborations with the neighboring Bio informatics Centre. Thus, the successful candidates will join a dynamic research environment with access to all modern facilities.
Scholarship Application Deadline:June 1, 2011.
Further Scholarship Information and Application
