Biology | Scholarship for Nigerians and Africans - Part 41

PhD in Neural Stem Cell Biology, University Muenster, Germany

The group for Stem Cell Biology & Regeneration at the ZMBE Institute of Cell Biology the Westphalian Wilhelms- University Muenster, Germany has an open Position for a PhD Student.
Applications are invited for a position within the group of Dr. Jens Schwamborn to investigate the mechanisms of fate specification in neural stem cells.
We investigate how the proliferation and differentiation of adult neural stem cells is regulated. In particular, we are interested in the question how the grade of differentiation of a cell is determined and how stem cell maintenance works. Further on we try to find ways to reprogram differentiated cells back into somatic stem cells. The overall aim of our work is to make endogenously present adult neural stem cells applicable for therapeutic approaches aiming for the replacement of neurons that are lost during neurodegenerative diseases (e.g. Parkinson’s disease).

Successful applicants should have a strong interest in Cell and Neurobiology, particularly experience in Stem Cell Biology would be a plus. We are looking for highly motivated people who share our passion for research, are interested in aquiring new skills and wish to be part of an international team.

Please send your application via E-Mail to: jschwamb@uni-muenster.de

Contact Person and Address :

Dr. Jens C. Schwamborn
Westfälische Wilhelms-Universität Münster
ZMBE, Institute of Cell Biology
Stem Cell Biology and Regeneration group
Von-Esmarch-Str. 56
48149 Münster
Germany
Phone: +49-251-83-57183
E-Mail: jschwamb@uni-muenster.de

Application deadline: 15.09.2010

PhD Position in Excellence Cluster Cellular Networks, University of Heidelberg, Germany

Integrins are the main receptors for cell-matrix adhesion and are continuously Trafficked within the cell.. An exact understanding of the cellular networks regulating integrin trafficking is missing, but is crucial for clarifying how cells respond to adhesive clues in their environment and Thus for understanding many vital processes, including cell migration or virus uptake. We will combine here methods from cell and molecular biology, systems biology, theoretical biophysics and bioinformatics to reconstruct the cellular networks regulating integrin trafficking. We offer a highly stimulating and international research environment at CellNetworks. We here will combine methods from cell and molecular biology, systems biology, theoretical biophysics and bioinformatics to reconstruct the cellular networks regulating integrin trafficking. We offer a highly stimulating and international research environment at CellNetworks. All three PhD-students will work in the BioQuant-building in the science campus Im Neuenheimer Feld. All three PhD students will work in the BioQuant-building in the science campus in the Neuenheimer Feld. Further information on CellNetworks and details of its research areas can be found at: www.cellnetworks.uni-heidelberg.de. Further information on CellNetworks and details of its research areas can be found at: www.cellnetworks.uni-heidelberg.de.

Conditions:
Applicants should indicate the research area they are applying for and send a detailed CV including a short summary of their research experiences and interests, copies of certificates as well as the name and contact details of two referees, by e-mail as a single PDF file no later than August 31, 2010 to: Applicants should indicate the research area they are applying for and send a detailed CV including a short summary of their research experiences and interests, copies of certificates as well as the name and contact details of two referees, by e-mail as a single PDF file no later than August 31, 2010 to:
Miscellaneous: Dr. Vytaute Starkuviene-Erfle, VIROQUANT, Im Neuenheimer Feld 267, 69120 Heidelberg Email: vytaute.starkuviene @ bioquant.uni-heidelberg.de Tel +49 6221 54 51 2599431

Prof. Dr. Ulrich Schwarz, Institute for Theoretical Physics, Philosophenweg 19, 69120 Heidelberg, Email ulrich.schwarz @ bioquant.uni-heidelberg.de Tel +49 6221 54 9431
Prof. Dr. Rob Russell, CellNetworks, Im Neuenheimer Feld 267, 69120 Heidelberg, Email: yvonne.lara @ bioquant.uni-heidelberg.de Tel +49 6221 54 513 61
Heidelberg University is an Equal Opportunity Employer and strongly encourages female candidates and handicapped persons to apply.

Postdoctoral Position:In Vivo and in Vitro Analysis of Molecular Mechanisms of Chromosome Segregation, Germany

Applications are invited for the postdoctoral position.
The mitotic spindle is a dynamic machine that segregate the replicated chromosomes between the two daughter cells during cell division. In anaphase a shrinking kinetochore microtubules move the chromosomes towards the spindle poles. Concurrently, the spindle midzone is formed in the centre of the spindle by overlapping microtubules where microtubule-bundling proteins (Ase1), kinesin motor proteins (Cin8 and Kip1), chromosomal passenger proteins (separase-Slk19), +TIPs (Bim1/EB1, Stu1/CLASP, Bik1/CLIP-170, Stu2/XMAP215) and signaling molecules (Aurora B kinase) localize 1-5. The spindle midzone stabilizes the anaphase spindle in all eukaryotic cells by crosslinking microtubules of the two half spindles It also drives spindle elongation in anaphase B and regulates cleavage furrow formation during cytokinesis in animal cells. The aim of this project is to study the biochemical properties of spindle midzone proteins using TIRF microscopy assays. Findings will be verified in the cell system using cell and molecular biology methods.
Conditions We are looking for a highly motivated scientist with a strong background in biochemistry, cell biology or molecular biology. The successful candidate will be part of an international, highly motivated team of PhD students and postdocs that works at the forefront of scientific research. Sonstiges: Miscellaneous: Please send written applications (CV, letter of motivation, transcripts) with 2-3 names of references to Prof. Dr. Elmar Schiebel, ZMBH, University of Heidelberg, INF 282, 69120 Heidelberg, Germany (schiebel.elmar@zmbh.uni-heidelberg.de).:
Application to: 13-08-2010