uni heidelberg | Scholarship for Nigerians and Africans

PhD Position in Excellence Cluster Cellular Networks, University of Heidelberg, Germany

Integrins are the main receptors for cell-matrix adhesion and are continuously Trafficked within the cell.. An exact understanding of the cellular networks regulating integrin trafficking is missing, but is crucial for clarifying how cells respond to adhesive clues in their environment and Thus for understanding many vital processes, including cell migration or virus uptake. We will combine here methods from cell and molecular biology, systems biology, theoretical biophysics and bioinformatics to reconstruct the cellular networks regulating integrin trafficking. We offer a highly stimulating and international research environment at CellNetworks. We here will combine methods from cell and molecular biology, systems biology, theoretical biophysics and bioinformatics to reconstruct the cellular networks regulating integrin trafficking. We offer a highly stimulating and international research environment at CellNetworks. All three PhD-students will work in the BioQuant-building in the science campus Im Neuenheimer Feld. All three PhD students will work in the BioQuant-building in the science campus in the Neuenheimer Feld. Further information on CellNetworks and details of its research areas can be found at: www.cellnetworks.uni-heidelberg.de. Further information on CellNetworks and details of its research areas can be found at: www.cellnetworks.uni-heidelberg.de.

Conditions:
Applicants should indicate the research area they are applying for and send a detailed CV including a short summary of their research experiences and interests, copies of certificates as well as the name and contact details of two referees, by e-mail as a single PDF file no later than August 31, 2010 to: Applicants should indicate the research area they are applying for and send a detailed CV including a short summary of their research experiences and interests, copies of certificates as well as the name and contact details of two referees, by e-mail as a single PDF file no later than August 31, 2010 to:
Miscellaneous: Dr. Vytaute Starkuviene-Erfle, VIROQUANT, Im Neuenheimer Feld 267, 69120 Heidelberg Email: vytaute.starkuviene @ bioquant.uni-heidelberg.de Tel +49 6221 54 51 2599431

Prof. Dr. Ulrich Schwarz, Institute for Theoretical Physics, Philosophenweg 19, 69120 Heidelberg, Email ulrich.schwarz @ bioquant.uni-heidelberg.de Tel +49 6221 54 9431
Prof. Dr. Rob Russell, CellNetworks, Im Neuenheimer Feld 267, 69120 Heidelberg, Email: yvonne.lara @ bioquant.uni-heidelberg.de Tel +49 6221 54 513 61
Heidelberg University is an Equal Opportunity Employer and strongly encourages female candidates and handicapped persons to apply.

Postdoctoral Position:In Vivo and in Vitro Analysis of Molecular Mechanisms of Chromosome Segregation, Germany

Applications are invited for the postdoctoral position.
The mitotic spindle is a dynamic machine that segregate the replicated chromosomes between the two daughter cells during cell division. In anaphase a shrinking kinetochore microtubules move the chromosomes towards the spindle poles. Concurrently, the spindle midzone is formed in the centre of the spindle by overlapping microtubules where microtubule-bundling proteins (Ase1), kinesin motor proteins (Cin8 and Kip1), chromosomal passenger proteins (separase-Slk19), +TIPs (Bim1/EB1, Stu1/CLASP, Bik1/CLIP-170, Stu2/XMAP215) and signaling molecules (Aurora B kinase) localize 1-5. The spindle midzone stabilizes the anaphase spindle in all eukaryotic cells by crosslinking microtubules of the two half spindles It also drives spindle elongation in anaphase B and regulates cleavage furrow formation during cytokinesis in animal cells. The aim of this project is to study the biochemical properties of spindle midzone proteins using TIRF microscopy assays. Findings will be verified in the cell system using cell and molecular biology methods.
Conditions We are looking for a highly motivated scientist with a strong background in biochemistry, cell biology or molecular biology. The successful candidate will be part of an international, highly motivated team of PhD students and postdocs that works at the forefront of scientific research. Sonstiges: Miscellaneous: Please send written applications (CV, letter of motivation, transcripts) with 2-3 names of references to Prof. Dr. Elmar Schiebel, ZMBH, University of Heidelberg, INF 282, 69120 Heidelberg, Germany (schiebel.elmar@zmbh.uni-heidelberg.de).:
Application to: 13-08-2010