research environment | Scholarship for Nigerians and Africans - Part 5

Postdoctoral Position Ambulatory Real-time Detection of Major Epileptic Seizures, Netherlands

Technische Universiteit Eindhoven (TU/e) is one of Europe’s leading research universities. The Eindhoven area, in the southern part of the Netherlands, is one of Europe’s top ‘innovation ecosystems’, with many high-tech companies and institutes. TU/e is closely intertwined with many of these companies and institutes, and research at TU/e is characterized by a combination of academic excellence and industrial relevance. Culturally, the Netherlands is a very interesting part of Europe. Historic cities such as Amsterdam, The Hague, Maastricht, Brussels, and Antwerp are all within easy reach from Eindhoven.

Kempenhaeghe is an internationally leading expertise centre for epilepsy and sleep-wake disorders. Kempenhaeghe is involved in nearly all major domains of epilepsy research, and offers a multidisciplinary semi-academic clinical research environment in the Eindhoven area. One of the innovation programmes in the area of diagnosis focuses on the detection of epileptic events, called seizures.

Project description

The goal of the ‘seizure detection programme’ is to achieve increased safety for the patient and a better quality of life for them and their loved ones by offering reliable, unobtrusive detection of epileptic seizures. Epilepsy has many different types of seizures, ranging from minor very short to major life-threatening seizures; every type has its own characteristics. The golden standard for detection of epileptic seizures uses combined EEG and video monitoring. This process is time-consuming, expensive, and only applicable to hospitalized patients. In order to overcome these problems and widen the reach of seizure detection to extramural patients, dependable unobtrusive approaches are critically needed. In past collaborative research, Kempenhaeghe and TU/e have gained important experience in detecting seizures based on analysis of heart activity and based on accelerometers attached to various parts of the body. Building on this experience, this PostDoc project seeks to develop and validate an unobtrusive system for detection of major epileptic seizures, and to iteratively refine it to approach the dependability of the aforementioned golden standard.

The main scientific focus will be on the development of dynamic models that characterize epileptic heart activity, epileptic movements, and the key sensor characteristics and (e.g. movement) artifacts, along with sophisticated multimodal model-based signal-processing and interpretation algorithms to extract reliable seizure information in ambulatory settings. The project will take a clinically driven approach, i.e. working in close collaboration with neurologists and medical technicians and taking their experience and knowledge as starting point. Algorithm development and validation will be based on real clinical data from patients. To obtain adequate clinical immersion, the candidate is expected to spend a significant fraction of his/her time at Kempenhaeghe, while TU/e will be the home base for algorithm development.

Requirements

Candidates for this position should have a Ph.D. degree in signal processing or control, physics, or biomedical engineering, and an extensive publication record in leading journals. A strong mathematical basis and a background in signal processing (statistical and adaptive signal processing, pattern recognition and machine earning, efficient real-time implementation of signal processing algorithms) is required. Hands-on experience with physiological monitoring and ambulatory sensor systems is desired, as are good programming skills in Matlab and C++. Candidates should be pro-active and entrepreneurial, have a ‘hands-on’ attitude, and excellent social and team working skills.

What we offer

A challenging job with a combined appointment at a multidisciplinary clinical expertise centre and a dynamic and ambitious University. A temporary appointment for the period of 3 years. Gross monthly salaries are in accordance with the Collective Labor Agreement (CAO) and are at least € 2988 per month (FWG 60) and at most € 4705 per month (scale 12). Salary is based on knowledge and experience. An attractive package of fringe benefits (including excellent work facilities, child care, and excellent sports facilities).

Application Deadline 29-08-2010.
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PhD Position: Knowledge and Capacity Development in the Water Sector, Netherlands

The Department of Hydroinformatics and Knowledge Management (HIKM) has a Core that is engaged in the study and application of Knowledge and Capacity Development (KCD). Current research concerns the modes of knowledge sharing in water resources, the capacity in government and the civil service system, and the access to the global knowledge pool through formal and informal learning processes and networks.

The vacancy is part of a new initiative to study how the effectiveness of KCD can be increased, and to help mainstream research outcomes in policy on international development. This effort is financed by the Netherlands government. For the Department we are looking for a Junior Researcher, Knowledge and Capacity Development in the Water Sector (m/f).

Responsibilities
As part of the KCD team, the (full time) researcher will conduct an academically rigorous study over about 4 years on the relationship between the capacity of the water sector and the sector’s performance in service delivery and water resource management, in about 6 countries, in a transversal analysis. The methodology will be based on the experiences and tools developed by the team and by other research groups. The approach in the study will include the selection of representative case studies, of which the development and performance will be the KCD activities and programs, the collection of quantitative data and information as well as narratives, and the comparative analysis of the KCD development dynamics in relation to KCD initiatives and programs. The study will establish a method to analyze the modes in which KCD affects the capacity and performance of the main organizations of the sub-sector, and how it helps to achieve benchmarks that are to be determined by the study.

The outputs of the study include (i) a set of peer-reviewed publications that are to be of adequate quality to allow the researcher to obtain his/her Doctor degree under Dutch law, and (ii) elaborate guidelines, and building blocks for KCD action plans and policy inputs that are relevant for international development. The researcher will, beside his/her research, prepare policy documents and reports to disseminate the results and recommendations, and will participate in relevant workshops and forums. In addition, he/she will prepare and give classes at post-graduate level for international course participants, and over time take leadership in the development of new educational programs. He/she will be staff member of the Core on KCD and work under the supervision of the Professor/Chair of KCD.

Requirements and Competencies
The candidate will:
* Have an education at MSc level or equivalent in water or water resources sciences or engineering, or in relevant social or economic sciences. Combination of degrees would create a special advantage. He/she should qualify for acceptance into a PhD programme under Dutch academic regulations.
* Have professional experience of at least three years in a related field in a utility, in a consultancy, government agency, or similar organization, and/or in a research environment. Experience with developing countries will be considered especially valuable.
* Be proficient in English, also for writing scientific papers, and, preferable, policy reports.
* Be able to work in a team and contribute to the teamwork.
* Bring a constructive attitude, and enthusiasm for the goal of knowledge management and international development.

Preference exists for candidates from developing countries.
Conditions of employment
This position is for four years, however, after about half a year a satisfactory detailed work proposal needs to be submitted, after which the appointment will be confirmed. The position is based in Delft, The Netherlands. The PhD research fellowship includes a monthly allowance of about €1190, air travel, health insurance, ancillary expenses and tuition. Candidates must be prepared to carry out long- and short-term missions abroad.

Information and application
Additional information can be obtained from Mr. Jan Luijendijk, Head of Department (T: +31(0)15- 21 51 810 / E: j.luijendijk@unesco-ihe.org).

Applications with curriculum vitae can be sent until August 31, 2010 to UNESCO-IHE, attn. Mr. Jan Luijendijk, Head of Department stating the vacancy description.


PhD Position in Excellence Cluster Cellular Networks, University of Heidelberg, Germany

Integrins are the main receptors for cell-matrix adhesion and are continuously Trafficked within the cell.. An exact understanding of the cellular networks regulating integrin trafficking is missing, but is crucial for clarifying how cells respond to adhesive clues in their environment and Thus for understanding many vital processes, including cell migration or virus uptake. We will combine here methods from cell and molecular biology, systems biology, theoretical biophysics and bioinformatics to reconstruct the cellular networks regulating integrin trafficking. We offer a highly stimulating and international research environment at CellNetworks. We here will combine methods from cell and molecular biology, systems biology, theoretical biophysics and bioinformatics to reconstruct the cellular networks regulating integrin trafficking. We offer a highly stimulating and international research environment at CellNetworks. All three PhD-students will work in the BioQuant-building in the science campus Im Neuenheimer Feld. All three PhD students will work in the BioQuant-building in the science campus in the Neuenheimer Feld. Further information on CellNetworks and details of its research areas can be found at: www.cellnetworks.uni-heidelberg.de. Further information on CellNetworks and details of its research areas can be found at: www.cellnetworks.uni-heidelberg.de.

Conditions:
Applicants should indicate the research area they are applying for and send a detailed CV including a short summary of their research experiences and interests, copies of certificates as well as the name and contact details of two referees, by e-mail as a single PDF file no later than August 31, 2010 to: Applicants should indicate the research area they are applying for and send a detailed CV including a short summary of their research experiences and interests, copies of certificates as well as the name and contact details of two referees, by e-mail as a single PDF file no later than August 31, 2010 to:
Miscellaneous: Dr. Vytaute Starkuviene-Erfle, VIROQUANT, Im Neuenheimer Feld 267, 69120 Heidelberg Email: vytaute.starkuviene @ bioquant.uni-heidelberg.de Tel +49 6221 54 51 2599431

Prof. Dr. Ulrich Schwarz, Institute for Theoretical Physics, Philosophenweg 19, 69120 Heidelberg, Email ulrich.schwarz @ bioquant.uni-heidelberg.de Tel +49 6221 54 9431
Prof. Dr. Rob Russell, CellNetworks, Im Neuenheimer Feld 267, 69120 Heidelberg, Email: yvonne.lara @ bioquant.uni-heidelberg.de Tel +49 6221 54 513 61
Heidelberg University is an Equal Opportunity Employer and strongly encourages female candidates and handicapped persons to apply.